Genomics and Pharmacogenomics

Wang have been well trained in bioinformatics and population genetics. Wang research interests focus on some basic questions using Tetrahymena thermophila as a model system. Based on professional skills in Bioinformatics and omics data analysis, he have made a direct contribution to reveal some important biological process or pathway in Tetrahymena and other ciliated protozoa through genome or transcriptome sequencing. Wang early publications have revealed that germline-limited sequences in Tetrahymena can encode genes with specific expression patterns and development-related functions during Tetrahymena MAC development. Wang also helps to demonstrate a facultative pathogen ciliate, Pseudocohnilembus persalinus, may gain its virulence through horizontal gene transfer. In addition, by integrating different kinds of omics data,and he helps to construct functional genomics database of Tetrahymena.